P0300 — Random/Multiple Cylinder Misfire Detected

Powertrain (engine/transmission)

P0300 indicates a random or multiple cylinder misfire has been detected by the engine control module (ECM). This means that the engine is experiencing combustion issues in various cylinders, not limited to a single cylinder.

The powertrain control module (PCM)/ECM monitors engine speed fluctuations to detect misfires across multiple engine cylinders, ensuring efficient combustion and preventing catalytic converter damage.

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Can I drive with P0300?

Drive as little as possible and book an inspection promptly.

Likely root causes

  • Vacuum leaks (e.g., intake manifold gasket, vacuum hoses)
  • Failing fuel injectors or fuel pump (leading to lean condition starvation)
  • Faulty mass airflow (MAF) sensor or oxygen (O2) sensor (providing incorrect air/fuel mixture data)

Common symptoms with P0300

  • Engine runs rough

Full symptom matching, likelihood scoring and related codes for your specific vehicle require a diagnosis.

Frequently asked questions

What does fault code P0300 mean?

P0300 means Random/Multiple Cylinder Misfire Detected.

Can I keep driving with P0300?

Drive as little as possible and book an inspection promptly.

What symptoms are common with P0300?

Engine runs rough

Related fault codes

  • P0301 — Cylinder 1 Misfire Detected
  • P0302 — Cylinder 2 Misfire Detected
  • P0303 — Cylinder 3 Misfire Detected
  • P0304 — Cylinder 4 Misfire Detected
  • P0305 — Cylinder 5 Misfire Detected
  • P0306 — Cylinder 6 Misfire Detected
  • P0307 — Cylinder 7 Misfire Detected
  • P0308 — Cylinder 8 Misfire Detected
  • P0309 — Cylinder 9 Misfire Detected

Get a full diagnosis for P0300 with AutoUncover.